QIBA Lung Nodule Profile Calculator (v0.1)

Welcome to the QIBA Lung Nodule Profile Calculator. The QIBA Lung Nodule Profile, when completed, will make claims about the confidence with which lung nodule volume and changes in lung nodule volume can be measured under a set of defined image acquisition, processing, and analysis conditions. This prototype calculator will allow users of the completed profile to obtain guidance on volumetric measurement error for user entered volumetric lesion measurements. Additional information on the draft QIBA lung nodule profile can be found here. If you encounter any issue with this calculator or have comments, please send email to info@accumetra.com.

THIS PROTOTYPE CALCULATOR AND THE RESULTS OBTAINED ARE FOR RESEARCH AND SCIENTIFIC PURPOSES ONLY AT THIS TIME. THE INFORMATION SHOULD NOT BE USED FOR PATIENT CARE.

Nodule Measurements

Enter a pair of numeric measurements for two sequential volume measurements of the same lung nodule in the yellow highlighted text boxes. The Time 1 volume measurement must be greater than or equal to 113 mm3 and less than 905 mm3. After valid numeric volume measurement values have been entered for Time 1 and Time 2, the numeric values throughout the remainder of the calculator will be updated.

Time 1 Measured Volume (mm3):
Time 2 Measured Volume (mm3):
Measured Volume Change (mm3):
Measured Volume Change (%):

QIBA Claim Guidance

This section provides specific information related to the precision of volumetric measurements with the provision that all profile requirements have been met.

Claim 1:

The "Time 1 Measured Volume 95% CI" values within this section provide the minimum and maximum values for the Time 1 volume measurement, with 95% confidence. You can think of this minimum to maximum range as error bars on the Time 1 volume measurement.

Minimum Maximum
Time 1 Measured Volume 95% CI (mm3):

Claim 2:

This section provides the minimum percentage of volume change necessary from Time 1 to represent a true change (A) and the 95% confidence interval for the amount of change measured (B). You may consider this latter range to represent error bars on the volume change measurement observed.

(A) Minimum
Minimum Volume Change 95% CI (%) :

(B) Minimum Maximum
Volume Change 95% CI (mm3):

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